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Angel & Pre-Seed Investments

Investing in early-stage biotech with durable conviction.

PC&H is a specialized investment firm focused on technically differentiated biotechnology startups. We partner with founders through key inflection points.

Stage
Angel → A
Style
Founder First

Nanoparticle Technologies

Nanoparticles are revolutionizing drug delivery, diagnostics, and therapeutics. We're particularly excited about lipid nanoparticles (LNPs), polymeric systems, and inorganic nanocarriers.

Drug Delivery

LNPs, exosomes, and targeted carriers for RNA and gene therapies

Targeted Therapeutics

Tumor-targeting nanoparticles and tissue-specific delivery

Nano-Diagnostics

Quantum dots and contrast agents for imaging and detection

Medical Technology

We back innovative medical devices and technologies that improve patient outcomes, reduce healthcare costs, and transform clinical practice.

Medical Devices

Implantables, surgical robotics, and next-gen diagnostics

Remote Monitoring

Wearables, continuous sensors, and connected health platforms

Surgical Innovation

Minimally invasive tools and AI-assisted procedures

Aging & Longevity

We're excited about the science of aging and companies working to extend healthspan. From senolytics to cellular reprogramming, this field is poised for breakthroughs.

Cellular Rejuvenation

Reprogramming, senolytics, and mitochondrial therapies

Aging Biomarkers

Epigenetic clocks, proteomics, and biological age testing

Healthspan Extension

Interventions targeting age-related decline and disease prevention

Therapeutics

Biologics, small molecules, cell and gene therapies with clear paths to clinical proof.

Platform Biotech

Repeatable discovery engines and scalable production technologies.

AI × Healthcare

Machine learning for drug discovery and clinical decision support.

Medical Devices

Innovative devices and surgical technologies improving outcomes.

Diagnostics

Point-of-care testing, liquid biopsy, and precision medicine tools.

Digital Health

Remote monitoring and software that improves care delivery.

What We Look For

Clear scientific hypothesis supported by early evidence
Credible path to value-defining milestones
Strong technical leadership and thoughtful governance
Development realism (regulatory, CMC, clinical)
Capital discipline without compromising rigor
Teams that communicate clearly and learn quickly
February 2026

Welcome to PC&H

Introducing Pharmaceutical Care & Health — a new investment firm focused on early-stage biotech innovation.

Read more